Menopausal status | Premenopausal | Postmenopausal | Pre-/postmenopausal | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRCA status | BRCA1 | BRCA2 | BRCA1 | BRCA2 | BRCA1/2 | ||||||||
Breast cancer | Unaffected | Affected | Total | Unaffected | Affected | Total | Unaffected | Affected | Total | Unaffected | Affected | Total | Total |
Number | n = 2729 | n = 1528 | n = 4257 | n = 1765 | n = 836 | n = 2601 | n = 451 | n = 199 | n = 650 | n = 327 | n = 179 | n = 506 | n = 6858 |
Age at Censoring | 38.2 ± 9.0 | 37.5 ± 6.7 | 37.9 ± 8.2 | 39.9 ± 8.9 | 39.9 ± 6.6 | 39.9 ± 8.2 | 53.4 ± 9.0 | 54.2 ± 8.0 | 53.7 ± 8.7 | 57.4 ± 8.8 | 56.0 ± 7.2 | 56.9 ± 8.3 | 40.5 ± 10.6 |
Year of Birth, no (%) | |||||||||||||
 < 1950 | 581 (21.3) | 332 (21.7) | 913 (21.4) | 465 (26.3) | 182 (21.8) | 647 (24.9) | 218 (48.3) | 150 (75.4) | 368 (56.6) | 205 (62.7) | 136 (76.0) | 341 (67.4) | 1560 (22.7) |
1950–1959 | 552 (20.2) | 529 (34.6) | 1081 (25.4) | 343 (19.4) | 295 (35.3) | 638 (24.5) | 148 (32.8) | 39 (19.6) | 187 (28.8) | 88 (26.9) | 41 (22.9) | 129 (25.5) | 1719 (25.1) |
1960–1969 | 748 (27.4) | 487 (31.9) | 1235 (29.0) | 456 (25.8) | 283 (33.9) | 739 (28.4) | 79 (17.5) | 8 (4.0) | 87 (13.4) | 31 (9.5) | 2 (1.1) | 33 (6.5) | 1974 (28.8) |
 ≥ 1970 | 848 (31.1) | 180 (11.8) | 1028 (24.1) | 501 (28.4) | 76 (9.1) | 577 (22.2) | 6 (1.3) | 2 (1.0) | 8 (1.2) | 3 (0.9) | 0 (0.0) | 3 (0.6) | 1605 (23.4) |
Height (cm) | 164.9 ± 6.9 | 164.6 ± 6.6 | 164.8 ± 6.8 | 164.3 ± 6.8 | 164.6 ± 7.0 | 164.4 ± 6.8 | 163.6 ± 6.9 | 162.1 ± 6.6 | 163.1 ± 6.8 | 162.6 ± 6.7 | 162.3 ± 6.3 | 162.5 ± 6.5 | 164.2 ± 6.6 |
Young adult* | |||||||||||||
Weight (kg) | 57.5 ± 8.9 | 56.1 ± 7.9 | 57.0 ± 8.6 | 57.9 ± 9.8 | 56.6 ± 7.9 | 57.5 ± 9.2 | 56.8 ± 8.2 | 56.1 ± 8.3 | 56.6 ± 8.2 | 57.9 ± 11.4 | 55.8 ± 8.5 | 57.2 ± 10.5 | 57.2 ± 8.8 |
BMI (kg/m2) | 21.1 ± 3.0 | 20.7 ± 2.6 | 21.0 ± 2.9 | 21.4 ± 3.3 | 20.9 ± 2.6 | 21.3 ± 3.1 | 21.2 ± 2.8 | 21.4 ± 2.9 | 21.3 ± 2.8 | 21.9 ± 3.9 | 21.2 ± 2.9 | 21.6 ± 3.6 | 21.1 ± 3.0 |