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Fig. 1 | Breast Cancer Research

Fig. 1

From: Noninvasive prediction of axillary lymph node breast cancer metastasis using morphometric analysis of nodal tumor microvessels in a contrast-free ultrasound approach

Fig. 1

HDMI image acquisition and a set of processing for image segmentation to extract vessel biomarkers: A HDMI image acquisition of ALN, B Microvasculature image of a metastatic ALN, C Defined ROI with 2 mm dilation of the ALN, D Conversion of the microvasculature image into a binary image, E skeleton image of vessel network, F HDMI biomarkers extracted for the skeleton to be used for distinguishing the metastatic ALN from reactive. HDMI: High definition microvessel imaging; ALN: Axillary lymph node; mvFD: Microvessel fractal dimension; NB: Number of branch points; VD: Vessel density; SVP: Spatial vascularity pattern; D: Diameter; τ: Tortuosity; NV: Number of vessel segments; MD: Murray’s deviation; VDR: Vessel density ratio; BA: Bifurcation angle.

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Breast Cancer Research

ISSN: 1465-542X

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