Skip to main content
Fig. 2 | Breast Cancer Research

Fig. 2

From: Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness

Fig. 2

Germline variants and PRS predicted lifetime risk (20–80 years) of breast cancer in high-risk familial breast cancer patients. Samples are ordered according to PRS score. a Age of diagnosis. b Germline variants possibly contributing to increased breast cancer family risk. Potential breast cancer predisposing genes were included if they are reported pathogenic/likely pathogenic in ClinVar. VUS were included for known moderate and high-risk genes. c Predicted lifetime risk of breast cancer by PRS score. The dashed line represents the mean lifetime risk (0–79 years) of breast cancer in the Danish population of 11.7% [51]

Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us