Fig. 5

miR-214-5P mimic downregulates RAD51 and induces HRD. A MDAMB468 cells were transfected with Dr-GFP and selected using 5 µg/ml puromycin. Stably expressing cells were transfected with ISCE-1 and analyzed for GFP⁺ cells using flow cytometry 48 h after transfection. B Histogram representation of GFP⁺ cells from three independent experiments with standard deviation as error bars. C MDAMB468 and D HCC1806 cells were transfected with miR-control or miR-214-5P and analyzed for protein expression using western blot (****p < 0.0001)