Fig. 3

The effect of attenuated TGFB signalling in macrophages on mammary gland morphogenesis. Representative mammary gland H&E-stained sections of doxycycline-treated single transgenic control Cfms-rtTA (n = 10; a), TetO-TbrII (n = 8; b), and double transgenic Cfms-TbrII (n = 12; c) mice at dioestrus. Examples of ductal epithelium are identified by arrows, and examples of alveolar epithelium are identified by arrowheads. The alveolar epithelium was quantified and expressed as a percentage of the total epithelium (d). Data are presented as mean + SEM with statistical analysis using a one-way ANOVA test, *p < 0.05, **p < 0.01