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Fig. 2 | Breast Cancer Research

Fig. 2

From: Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences

Fig. 2

SNV enrichments in ER-positive local recurrences. a OncoPrint of non-silent, enriched single nucleotide variants in patient-matched cases. Missense variants are indicated with a green box and nonsense variants with black. b Triplet mutation enrichment of PIK3CA mutations in case ERLR_01. Collapsed IGV alignments are shown, along with allele frequencies, for the normal, primary, and recurrence. c Frequency of enriched, non-silent single nucleotide variants versus time to recurrence along with Pearson R and calculated p value

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