Table 1 Distribution of patient characteristics and CAP1 expression
|  |  | Patients with tumor in TMA (n = 718) |  | ||||
|---|---|---|---|---|---|---|---|
Patient characteristics n (%) or median (IQR) | All patients (n = 910) | Low CAP1 (n = 106) | Moderate CAP1 (n = 273) | High CAP1 (n = 290) | Ptrend | Non-assessable (n = 49) | Not included in TMA (n = 192) |
Age at baseline | |||||||
 Continuous [years] | 55.4 (50.0–61.7) | 56.2 (51.9–62.2) | 56.2 (50.6–61.7) | 53.5 (49.0–59.4) | < 0.001a | 52.3 (48.2–57.4) | 58.2 (51.7–62.3) |
Menopause | |||||||
 Premenopausal | 68 (7.9) | 4 (3.9) | 21 (8.0) | 23 (8.3) | 0.216b | 5 (11.1) | 15 (8.5) |
 Postmenopausal | 792 (92.1) | 98 (96.1) | 240 (92.0) | 253 (91.7) | 40 (88.9) | 161 (91.5) | |
 Missing | 50 | 4 | 12 | 14 |  | 4 | 16 |
Height | |||||||
 Continuous [cm] | 165.0 (160.0–168.0) | 164.5 (161.0–167.3) | 164.0 (160.0–168.0) | 165.0 (161.0–169.0) | 0.091a | 163.0 (160.0–167.5) | 165.0 (161.0–168.0) |
Weight | |||||||
 Continuous [kg] | 68.0 (61.0–75.0) | 69.0 (60.8–77.3) | 69.0 (62.0–75.0) | 67.0 (61.0–74.0) | 0.060a | 65.0 (61.0–73.5) | 68.0 (62.3–75.0) |
BMI | |||||||
 Continuous [kg/m2] | 24.8 (22.8–27.8) | 25.1 (22.5–28.6) | 25.3 (23.1–28.5) | 24.4 (22.2–27.4) | 0.009a | 24.3 (22.8–27.6) | 24.7 (22.9–27.5) |
 < 25 | 466 (51.2) | 52 (49.0) | 126 (46.2) | 161 (55.5) | 0.053b | 30 (61.2) | 97 (50.5) |
 25–30 | 310 (34.1) | 34 (32.1) | 101 (37.0) | 91 (31.4) | 13 (26.5) | 71 (37.0) | |
 > 30 | 134 (14.7) | 20 (18.9) | 46 (16.9) | 38 (13.1) | 6 (12.2) | 24 (12.5) | |
Waist | |||||||
 Continuous [cm] | 77.0 (71.0–83.0) | 77.0 (71.0–85.3) | 78.0 (72.0–86.0) | 76.0 (70.0–83.0) | 0.008a | 76.0 (69.5–83.0) | 76.5 (71.0–82.0) |
 < 81 | 603 (66.3) | 64 (60.4) | 171 (62.6) | 197 (68.2) | 0.063b | 33 (67.3) | 138 (71.9) |
 81–85 | 116 (12.8) | 16 (15.1) | 30 (11.0) | 43 (14.9) | 7 (14.3) | 20 (10.4) | |
 > 85 | 190 (20.9) | 26 (24.5) | 72 (26.4) | 49 (16.9) | 9 (18.4) | 34 (17.7) | |
 Missing | 1 | 0 | 0 | 1 |  | 0 | 0 |
Hip | |||||||
 Continuous [cm] | 97.0 (91.0–103.0) | 98.0 (92.0–106.0) | 97.0 (91.0–104.0) | 96.0 (90.0–102.0) | 0.014a | 95.0 (90.0–103.0) | 97.0 (92.0–102.8) |
 Missing | 1 | 0 | 0 | 1 |  | 0 | 0 |
Waist-hip ratio | |||||||
 Continuous | 0.79 (0.76–0.83) | 0.79 (0.76–0.83) | 0.80 (0.77–0.83) | 0.79 (0.76–0.82) | 0.095a | 0.79 (0.75–0.84) | 0.78 (0.75–0.82) |
 ≤ 0.80 | 522 (57.4) | 63 (59.4) | 135 (49.5) | 175 (60.6) | 0.810b | 27 (55.1) | 122 (63.5) |
 0.81–0.84 | 268 (29.5) | 33 (31.1) | 100 (36.6) | 73 (25.3) | 14 (28.6) | 48 (25.0) | |
 ≥ 0.85 | 119 (13.1) | 10 (9.4) | 38 (13.9) | 41 (14.2) | 8 (16.3) | 22 (11.5) | |
 Missing | 1 | 0 | 0 | 1 |  | 0 | 0 |
Body fat percentage | |||||||
 Continuous [%] | 31.0 (27.8–34.0) | 31.5 (28.0–35.0) | 32.0 (28.0–35.0) | 30.0 (27.0–33.8) | 0.006a | 30.0 (26.0–34.0) | 31.0 (28.0–34.0) |
 ≤ 24 | 83 (10.3) | 9 (8.5) | 20 (7.4) | 46 (16.0) | 0.007b | 5 (10.2) | 13 (6.8) |
 25–31 | 395 (43.6) | 44 (41.5) | 114 (42.1) | 121 (42.0) | 23 (46.9) | 93 (48.4) | |
 ≥ 32 | 418 (46.1) | 53 (50.0) | 137 (50.6) | 121 (42.0) | 21 (42.9) | 86 (44.8) | |
 Missing | 4 | 0 | 2 | 2 |  | 0 | 0 |