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Table 3 Associations of percent density with overall breast cancer, by BMI and menopausal status for 1823 cases and 4720 controls

From: Body mass index, mammographic density, and breast cancer risk by estrogen receptor subtype

 

Normal/underweight

BMI < 25 kg/m2

Overweight/obese

BMI ≥ 25 kg/m2

 
 

Cases

Controls

Percent density

OR per S.D. (95% CI)a

Cases

Controls

Percent density

OR per S.D. (95% CI)a

P int b

Premenopausal

383

979

1.83 (1.54–2.18)

227

528

1.46 (1.22–1.74)

0.07

Postmenopausal HT user

281

678

1.64 (1.38–1.95)

198

446

1.61 (1.32–1.95)

0.84

Postmenopausal HT non-user

279

1029

1.46 (1.24–1.70)

455

1060

1.48 (1.30–1.69)

0.94

  1. Abbreviations: BMI body mass index, CI confidence interval, ER estrogen receptor, HT hormone therapy, OR odds ratio, S.D. standard deviation
  2. aOdds ratios estimated from polytomous multivariable logistic regression models adjusted for age, study. Standard deviation of square root-transformed percent density = 2.0
  3. bP value of test for BMI-percent density interaction