Fig. 1

Deleterious somatic mutations of IBC tumors and non-IBC tumors. a Deleterious somatic mutations of 156 IBC tumors. b Deleterious somatic mutations of 197 non-IBC tumors. Tumors with available mutation data are grouped by four molecular subtypes along the x axis, with the x axis also showing clinic characteristics for each tumor; the 91 genes of BreastCurie panel are enriched to 10 signaling on the y axis. The somatic mutations of each tumor are indicated by colored boxes: red boxes indicate pathogenic variants, and green boxes indicate unknown pathogenic variants. ER estrogen receptor, HER2 human epidermal growth factor receptor 2, HR hormone receptor, SBR Scarff Bloom Richardson classification, TNBC triple-negative breast cancer, TNM tumor node metastasis