Skip to main content

Table 3 OS univariate and multivariate analysis of immune parameters evaluated on metastasis biopsies of triple-negative breast cancer

From: Immune characterization of breast cancer metastases: prognostic implications

    Univariate Multivariate
Median OSmonths (95%CI) HR (95%CI) p HR (95%CI)
TILs Low ≤10% 11.8 (4.1–19.5) ref 0.012 ref
High > 10% 62.9 (52.3–73.5) 0.29 (0.11–0.76) 0.06 (0.01–0.29)
CD8/FOXP3 ratio 1st tertile 8.0 (0.0–17.1) ref 0.020 ref
2nd tertile 13.2 (0.0–28.3) 0.59 (0.22–1.58) 0.17 (0.05–0.59)
3rd tertile 54.0 (32.4–75.7) 0.20 (0.06–0.67) 0.03 (0.004–0.15)
  1. Abbreviations: OS overall survival, HR hazard ratio, p p value, TILs tumor-infiltrating lymphocytes
  2. Significant p values in bold