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Table 3 Longitudinal volume changes (in measured total intracranial volume (mTIV) ratio) within the chemotherapy group and the healthy control group

From: Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: a brain magnetic resonance imaging pilot study

 

Chemotherapy group (n = 16)

Healthy control group (n = 14)

p comparing groups*

changes in mTIV ratio (SD)

p value

changes in mTIV ratio (SD)

p value

 

Total white matter

1.65 (3.63)

0.06

0.90 (2.91)

0.32

0.54

Total gray matter

−2.05 (3.38)

0.02

−0.99 (3.18)

0.27

0.38

Frontal lobe

−0.33 (0.39)

0.003

−0.27 (0.44)

0.02

0.68

Temporal lobe

−0.09 (0.31)

0.16

0.08 (0.16)

0.25

0.08

Parietal lobe

−0.07 (0.27)

0.27

−0.08 (0.22)

0.23

0.89

Occipital lobe

0.01 (0.18)

0.77

−0.02 (0.14)

0.65

0.60

  1. *p values from comparison of volume changes between the two groups (group-by-time interaction)