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Table 5 Modelling results for screen-detected and interval cancer

From: A novel and fully automated mammographic texture analysis for risk prediction: results from two case-control studies

  Risk score Contrast Sum average 16 Sum average 32 Sum average 64 Volumetric PD
Standardized OR for screen-detected cancer 1.15 0.88 1.09 1.11 1.20 1.13
(0.99–1.35) (0.75–1.04) (0.93–1.26) (0.95–1.30) (1.02–1.40) (0.94–1.35)
Standardized OR for interval cancer 2.09 0.84 2.12 2.15 1.91 1.53
(1.59–2.74) (0.66–1.06) (1.59–2.81) (1.62–2.86) (1.48–2.47) (1.21–1.92)
Δχ2 15.27 0.15 18.53 17.84 9.80 4.38
P value 0.0001 0.70 <0.0001 <0.0001 0.002 0.036
  1. Standardized odds ratio (OR) is the change in odds for a standard deviation (in controls) increase in image features; the 95% confidence intervals are in brackets. Sum average 16, 32 and 64 are the texture feature sum average using images downsized by a factor of 16, 32 and 64
  2. The Δχ 2 and p values refer to likelihood-ratio tests on whether there is a significant difference between screen-detected and interval cancers (i.e. significance of interaction terms)
  3. PD percent density