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Fig. 4 | Breast Cancer Research

Fig. 4

From: Evaluation of invasive breast cancer samples using a 12-chemokine gene expression score: correlation with clinical outcomes

Fig. 4

Analysis of primary breast tumors with H&E staining and IHC. Representative high-chemokine-scored breast slide revealed a marked peritumoral lymphocytic host response, organized as ectopic lymph node-like structures (ELN) by H&E staining (a) and by IHC (be). The immunohistochemical analysis of the lymphoid population highlighted the CD3+, CD4+, and CD8+ T cells (b, c and d) distributed in the parafollicular cortex or marginal zones and with some dispersion into the follicles while CD20 + B cells are concentrated in the center of the follicles (e). Magnification × 200

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