Breast Cancer Research

Table 4 Spearman’s correlation (r) for continuous variables

From: Immune response in breast cancer brain metastases and their microenvironment: the role of the PD-1/PD-L axis

Variable		CD4	CD8	CD68	PD-L1	PD-L2
CD4	r	–	0.48	0.23	0.12	0.20
CD4	P	–	<0.001	0.043	0.311	0.088
CD8	r	0.48	–	0.27	0.13	0.19
CD8	P	<0.001	–	0.019	0.264	0.100
CD68	r	0.23	0.27	–	0.09	0.19
CD68	P	0.043	0.019	–	0.471	0.104
PD-L1	r	0.12	0.13	0.09	–	0.12
PD-L1	P	0.311	0.264	0.471	–	0.317
PD-L2	r	0.20	0.19	0.19	0.12	–
PD-L2	P	0.088	0.100	0.104	0.317	–
PD-1^a	r	0.26	0.33	0.06	−0.04	0.13
PD-1^a	P	0.028	0.005	0.617	0.742	0.267

PD-1 programmed cell death protein 1 receptor, PD-L1 programmed cell death protein 1 receptor ligand. ^aCategorical variable

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