From: Markers for the identification of late breast cancer recurrence
Score | Abbreviation | Details | Reference |
---|---|---|---|
MammaPrint | MammaPrint | 70 gene-based expression profile using DNA microarray. Fresh frozen material is used to perform analysis. | |
Genomic Grade Index | GGI | 97 gene-based assay using DNA micro array. Fresh frozen material is used to perform the analysis. | |
Oncotype Dx Recurrence Score | RS | 21 gene-based expression profile score using qRT-PCR (16 cancer genes, 5 housekeeping genes). FFPE blocks used to extract RNA. | [25] |
Immunohistochemical Score 4 | IHC4 | Includes information on estrogen receptor (ER), progesterone receptor (PgR), Ki67, and HER2. Score developed on transATAC data. FFPE blocks used to extract RNA to perform IHC for ER, PgR, Ki67, and HER2. | [31] |
Prosina Risk of Recurrence Score | ROR | 50 gene-based expression profile score using qRT-PCR. FFPE blocks used to extract RNA to perform analysis on nCounter system. | [34] |
Breast Cancer Index | BCI | Multi-gene assay using qRT-PCR. Combination of two biomarkers HOXB13/IL17BR (H/I) and molecular grade index (MGI). FFPE blocks used to extract RNA to perform analysis. | |
EndoPredict | EPclin | 12 gene-based expression profile score using qRT-PCR (8 cancer genes, 4 housekeeping genes). FFPE blocks used to extract RNA to perform analysis. | [41] |