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Figure 7 | Breast Cancer Research

Figure 7

From: DEAD-box protein p68 is regulated by β-catenin/transcription factor 4 to maintain a positive feedback loop in control of breast cancer progression

Figure 7

p68 knockdown reduces breast tumour volume and expression of EMT markers in mice. (a) p68 expression level was determined in p68 knockdown mouse 4T1 stable cells. Control short hairpin RNA (shRNA)-4T1 stable cells were kept as control. (b) Images of mouse breast tumours after 16 days of injections in the mammary fat pad regions with stable cells expressing either control shRNA or p68 shRNA. Tumours obtained from the mammary fat pad regions were analysed for tumour volume (right panel). (c) Images of the hematoxylin and eosin (H&E)-stained sections of the tumours and immunohistochemical analysis of the adjacent sections were performed with the indicated antibodies as shown in the figure. Images were captured at magnifications of 200X.

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Breast Cancer Research

ISSN: 1465-542X

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