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Figure 5 | Breast Cancer Research

Figure 5

From: Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays

Figure 5

Reporter responsive (RR) cells derived from primary patient breast tumors exhibit enhanced tumorigenic properties and elevated expression of target genes. (A) Representative anchorage-independent methylcellulose colony formation assay numerical and pictorial results from patients 11, 17, 18, and 19 reporter unresponsive (RU) and reporter responsive (RR) cell populations. (B). Quantitative-PCR PROM1, MUC15, and GPR49 mRNA transcript analysis of fluorescence-activated cell sorting-purified lentiviral Sox2 transcription activity reported-infected primary patient breast tumor RU and RR cells from patients 13 to 19.

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Breast Cancer Research

ISSN: 1465-542X

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