A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype

Table 3 Distribution of early or late recurrence-associated genes in different gene clusters

Cluster	Genes associated with	Correlation	Fisher’s exact test (Pvalue)	Odds ratio (OR)	95% confidence interval (95% CI)
C1	Early recurrence	direct	1.19 × 10⁻¹⁴	no probe set in C1
		inverse	2.41 × 10⁻²⁴	89.15	20.82 - 381.84
	Late recurrence	direct	0.0002	0.06	0.02 - 0.48
		inverse	0.1872	0.21	0.03 - 1.65
C2	Early recurrence	direct	0.3475	0.41	0.09 - 1.92
		inverse	8.81 × 10⁻⁷	5.96	2.77 - 12.83
	Late recurrence	direct	0.6402	1.28	0.53 - 3.08
		inverse	0.0744	no probe set in C2
C3	Early recurrence	direct	3.05 × 10⁻²⁶	39.14	17.42 - 87.95
		inverse	0.0468	0.02	0.01 - 0.05
	Late recurrence	direct	0.0057	0.27	0.10 - 0.73
		inverse	9.41 × 10⁻⁰⁵	21.52	2.72 - 170.15
C4	Early recurrence	direct	1	0.98	0.42 - 2.30
		inverse	1.50 × 10⁻⁰⁸	no probe set in C4
	Late recurrence	direct	1.48 × 10⁻¹¹	25.00	9.50 - 65.80
		inverse	0.3697	no probe set in C4

ISSN: 1465-542X