Quantitative determination, by real-time reverse transcription polymerase chain reaction, of aromatase mRNA in invasive ductal carcinoma of the breast

Table 1 Aromatase mRNA expression and clinicopathologic factors in patients with invasive ductal carcinoma

Factor	n	Aromatase mRNA (mean ± standard deviation)	P (Mann–Whitney U-test)
Age (years)
> 50	104	29 ± 60	0.0042*
≤ 50	58	14 ± 24
Axillary lymph node status
-	103	30 ± 62	0.010*
+	59	13 ± 20
Tumor size
< 2 cm	43	29 ± 54	0.042*
≥ 2 cm	119	22 ± 50
ER-α status
+	108	28 ± 59	0.0021*
-	47	13 ± 20
PgR status
+	87	24 ± 44	0.63
-	62	25 ± 63
Histologic grade
1 or 2	113	24 ± 50	0.11
3	49	24 ± 54

Estrogen receptor (ER)-α status and progesterone receptor (PgR) status were determined histochemically. *P < 0.05.

ISSN: 1465-542X