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Table 3 Multivariable analysis of RFS and OS for hormone receptor-positive breast cancer patients.

From: Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer

Recurrence-free survival

Variable

HR

95% CI

Pvalue

Age at diagnosis

1.00

0.97-1.03

0.951

Nodal status

   

   Negative

1

  

   Positive

3.08

1.66-5.73

<0.001

T stage

   

   T1

1

  

   T2-4

1.31

0.66-2.58

0.439

p4E-BP1 S65

1.62

1.13-2.31

0.008

Overall survival

Variable

HR

95% CI

P value

Age at diagnosis

1.04

1.01-1.07

0.003

Nodal status

   

   Negative

   

   Positive

1.29

0.75-2.23

0.355

T stage

   

   T1

   

   T2-4

1.02

0.58-1.81

0.945

pS6 S235/236

1.73

1.03-2.90

0.039

eEF2K

2.19

1.35-3.56

0.002

Pdcd4

0.42

0.25-0.70

0.001

  1. CI, confidence interval; HR, hazard ratio.