Skip to main content

Advertisement

Positive predictive value of MRI vacuum biopsies in the diagnosis of nonmass-like lesions of the breast

Article metrics

  • 1298 Accesses

Objective

To evaluate the positive predictive value of MRI scoring for malignant mass-like (ML) and nonmass-like (NML) lesions based on the BI-RADS descriptors. To identify MRI characteristics of nonmass lesions which predict malignancy for invasive and non-invasive cancers.

Methods

Retrospective analysis of 486 MRI-guided vacuum biopsies performed at Northwick Park Hospital between April 2006 and November 2011. Each lesion was categorised according to BI-RADS lexicon (ML vs. NML lesions) and time-enhancement curves, and given an overall score of MRI 1 to 5 according to overall level of suspicion for malignant disease where MRI 4 and 5 are considered suspicious or diagnostic for malignancy. Biopsy and surgical histology results obtained.

Results

A total of 291 ML and 152 NML lesions, of which there were 150 cancers diagnosed. Positive predictive value of MRI characteristic for malignant mass lesions is 70%. Positive predictive value of MRI characteristic for nonmass lesions is 57%. Segmental enhancement is the most common MRI morphology found in 45% DCIS. No specific features predict for invasive disease in NML lesions. Time-enhancement curves were mainly type 2 (44.6%) and type 3 (52.7%) in malignant ML lesions and unhelpful in predicting malignancy in NML lesions (72% type 2 and 59% type 3 were benign).

Conclusion

No specific BI-RADS feature predicts for invasive disease in NML lesions. Segmental enhancement is the most common MRI appearance for DCIS. Time-enhancement curves are unhelpful in predicting malignancy in NML lesions.

Author information

Correspondence to WL Teh.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Teh, W., Papantoniou, E. & Ng, F. Positive predictive value of MRI vacuum biopsies in the diagnosis of nonmass-like lesions of the breast. Breast Cancer Res 14, O3 (2012) doi:10.1186/bcr3252

Download citation

Keywords

  • Mass Lesion
  • Invasive Disease
  • Histology Result
  • Malignant Mass
  • Park Hospital