Table 7 Multivariate analysis of GP88 and combined risk factors on DFS and OS

HR

CI

P

HR

CI

P

GP88 (3+ vs. < 3+)

5.15

2.73 to 9.69

< 0.0001

1.84

1.13 to 3.00

0.0148

Ethnicity (Caucasian vs. non-Caucasian)

1.94

0.94 to 4.04

0.0744

1.03

0.57 to 1.86

0.9190

Age (> 50 yrs vs. ≤ 50 yrs)

0.66

0.34 to 1.30

0.2301

1.57

0.90 to 2.75

0.1101

Tumor size (> 2 cm vs. ≤ 2 cm)

1.06

0.50 to 2.23

0.8793

1.03

0.61 to 1.72

0.9257

Tumor size (> 5 cm vs. ≤ 5 cm)

0.44

0.09 to 2.29

0.3324

0.79

0.25 to 2.54

0.6979

Grade (> 1 vs. ≤ 1)

0.70

0.09 to 5.50

0.7309

0.54

0.16 to 1.86

0.3291

Grade (> 2 vs. ≤ 2)

0.80

0.41 to 1.57

0.5130

1.72

1.00 to 2.94

0.0501

Stage (> 1 vs. ≤ 1)

1.45

0.59 to 3.56

0.4211

2.52

1.23 to 5.14

0.0111

Stage (> 2 vs. ≤ 2)

4.21

1.78 to 9.93

0.0010

2.42

1.28 to 4.57

0.0065