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Table 1 Correlation of Pokemon expression with clinicopathological parametersa

From: Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression

 

Pokemon(n= 182)

 

Variables

3

2

1

0

Pvalue

Subtotal, n (%)

72 (39.6)

69 (37.9)

17 (9.3)

24 (13.2)

 

Age, yr (%)

    

0.2451

   >50

58 (40.8)

55 (38.7)

13 (9.2)

16 (11.3)

 

   ≤50

13 (33.3)

14 (35.9)

4 (10.3)

8 (20.5)

 

Tumor types, n (%)

    

0.8733

   Colloid

3 (37.5)

3 (37.5)

1 (12.5)

1 (12.5)

 

   Ductal

35 (47.9)

26 (35.6)

5 (6.8)

7 (9.6)

 

   Lobular

14 (53.8)

8 (30.8)

3 (11.5)

1 (3.8)

 

Tumor size, cm3 (%)

    

0.0148

   >2

47 (42.7)

46 (41.8)

9 (8.2)

8 (7.3)

 

   ≤2

23 (33.8)

22 (32.3)

8 (11.8)

15 (22.1)

 

Node metastasis, n (%)

    

0.0014

   Positive

49 (44.1)

38 (34.2)

8 (7.2)

16 (14.4)

 

   Negative

22 (31.9)

30 (43.5)

9 (13.0)

8 (11.6)

 

Nuclear grade, n (%)

    

0.057

   1

5 (23.8)

9 (42.6)

2 (9.5)

5 (23.8)

 

   2

40 (40.4)

38 (38.4)

12 (12.1)

9 (9.1)

 

   3

25 (45.5)

20 (38.4)

3 (12.1)

7 (9.1)

 

ER, n (%)

    

0.429

   Positive

38 (37.6)

39 (38.6)

11 (10.9)

13 (12.9)

 

   Negative

34 (42.0)

30 (37.0)

6 (7.4)

11 (13.6)

 

PR, n (%)

    

0.3444

   Positive

41 (40.2)

34 (33.3)

14 (13.7)

13 (12.8)

 

   Negative

31 (38.8)

35 (43.8)

3 (3.7)

11 (14.7)

 

HER2, n (%)

    

0.2309

   Positive

31 (38.7)

28 (35.0)

7 (8.8)

14 (17.5)

 

   Negative

41 (38.3)

41 (38.3)

11 (10.3)

14 (13.1)

 
  1. aData are from the Yale Tissue Microarray-23, in which 182 breast cancer cases were histologically interpretable and analyzed for the correlation of Pokemon expression with clinicopathological parameters. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.