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Figure 10 | Breast Cancer Research

Figure 10

From: Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations

Figure 10

Estrogen receptor transcriptional activity in BT474 cells. Estrogen receptor (ER) transcriptional activity in BT474 cells transiently co-transfected with 3× ERE-TATA luciferase and CMV-Renilla luciferase vectors following treatment with 1 μM Faslodex, 1 μM all-trans retinoic acid (atRA), 1 μg/ml trastuzumab (Tzmab), 1 μM tamoxifen (Tam), or their combinations. The firefly luciferase activities of the treated cells have been normalized to their Renilla luciferase activities and are expressed as a percentage of activity of untreated cells. Results are mean of three independent experiments ± standard error.

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