| No. women | No. cancers | No. pyears | IRR - binary (95% CI) P-value | IRR - trend (95% CI) P-value |
---|---|---|---|---|---|
Adjusted for age ≥ 45 years | |||||
MRI % dense volume | 655 | 56 | 4,328 | 1.68 (0.97, 2.94) 0.066 | 1.17 (0.92, 1.49) 0.21 |
Cumulus MLO % dense area | 607 | 42 | 4,109 | 1.12 (0.61, 2.05) 0.72 | 1.06 (0.81, 1.40) 0.66 |
VA MLO % dense area | 599 | 42 | 4,060 | 1.61 (0.87, 2.98) 0.13 | 1.25 (0.96, 1.64) 0.098 |
Adjusted for age ≥ 45 years, tamoxifen use, BMI and parity | |||||
MRI % dense volume | 503 | 40 | 3,381 | 1.32 (0.64, 2.73) 0.46 | 1.10 (0.79, 1.54) 0.56 |
Cumulus MLO % dense area | 456 | 30 | 3,123 | 0.89 (0.39, 2.03) 0.78 | 0.92 (0.63, 1.35) 0.68 |
VA MLO % dense area | 450 | 30 | 3,085 | 1.61 (0.71, 3.68) 0.26 | 1.22 (0.84, 1.76) 0.29 |
Adjusted for age ≥ 45 years and BRCA1/2 status/carrier probability | |||||
MRI % dense volume | 619 | 53 | 4,083 | 2.04 (1.16, 3.59) 0.013 | 1.30 (1.01, 1.67) 0.039 |
Cumulus MLO % dense area | 591 | 39 | 4,006 | 1.82 (0.96, 3.45) 0.065 | 1.26 (0.95, 1.68) 0.11 |
VA MLO % dense area | 583 | 39 | 3,957 | 2.24 (1.18, 4.26) 0.014 | 1.47 (1.11, 1.96) 0.008 |
Adjusted for age ≥ 45 years, BRCA1/2 status/carrier probability, BMI and parity | |||||
MRI % dense volume | 489 | 39 | 3,276 | 1.76 (0.82, 3.77) 0.15 | 1.26 (0.87, 1.81) 0.22 |
Cumulus MLO % dense area | 450 | 29 | 3,078 | 1.43 (0.62, 3.32) 0.41 | 1.09 (0.73, 1.63) 0.66 |
VA MLO % dense area | 444 | 29 | 3,040 | 1.84 (0.81, 4.19) 0.15 | 1.37 (0.94, 2.02) 0.11 |