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Table 3 Final model for multivariate analysis of MFS in ER+ lymph node-negative patient s 1

From: Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: a prognosis study

Characteristic HR (95% CI) P
Age (years)   
   41-55 vs. ≤ 40 0.72 (0.49-1.06) 0.101
   56-70 vs. ≤ 40 0.43 (0.28-0.65) < 0.001
   >70 vs. ≤ 40 0.44 (0.28-0.70) 0.001
Tumor size   
   pT2 vs. pT1 1.41 (1.07-1.84) 0.013
   pT3/4 vs. pT1 1.82 (0.95-3.51) 0.073
Grade   
   Good/moderate vs. Poor 0.58 (0.38-0.87) 0.009
   Unknown vs. Poor 1.05 (0.79-1.39) 0.729
SIPA1 rs2448490   
   AA vs. AG+GG 0.56 (0.38-0.85) 0.006
RRP1B rs9306160   
   CT+TT vs. CC 0. 71 (0.54-0.92) 0.011
  1. 1761 patients
  2. CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; MFS = metastasis-free survival.