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Table 3 Final model for multivariate analysis of MFS in ER+ lymph node-negative patient s 1

From: Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: a prognosis study

Characteristic

HR (95% CI)

P

Age (years)

  

   41-55 vs. ≤ 40

0.72 (0.49-1.06)

0.101

   56-70 vs. ≤ 40

0.43 (0.28-0.65)

< 0.001

   >70 vs. ≤ 40

0.44 (0.28-0.70)

0.001

Tumor size

  

   pT2 vs. pT1

1.41 (1.07-1.84)

0.013

   pT3/4 vs. pT1

1.82 (0.95-3.51)

0.073

Grade

  

   Good/moderate vs. Poor

0.58 (0.38-0.87)

0.009

   Unknown vs. Poor

1.05 (0.79-1.39)

0.729

SIPA1 rs2448490

  

   AA vs. AG+GG

0.56 (0.38-0.85)

0.006

RRP1B rs9306160

  

   CT+TT vs. CC

0. 71 (0.54-0.92)

0.011

  1. 1761 patients
  2. CI = confidence interval; ER = estrogen receptor; HR = hazard ratio; MFS = metastasis-free survival.
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Breast Cancer Research

ISSN: 1465-542X

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