Disseminated tumor cells |
   As a prognostic marker (M0) |
   As an indicator for secondary adjuvant therapya |
   For optimization of 'secondary' adjuvant therapy based on the genotype and phenoytpe of the disseminated tumor cellsa |
Circulating tumor cells |
   As a prognostic marker (M1) |
   For therapy monitoring (M1) a |
   For early therapy response to palliative treatment (M1)a |
   For reassessment of therapeutic markers by characterization of circulating tumor cells (real time biopsy)a |