Table 2 PALB2 mutations identified in early-onset French-Canadian women with breast cancer and their frequencies in newborn controls
PALB2 variant | Frequency in cases (percentage) | Frequency in controls (percentage) | P value |
|---|---|---|---|
Q775X | 2/356 (0.56) | 0/6,440 (0) | 0.0027 |
I76V | 0/356 (0) | 0/6,442 (0) | - |
G115V | 1/356 (0.28) | 15/6,442 (0.12) | 0.99 |
All variants | 3/356 | 15/6,442 | 0.065 |