Table 2 Cytokines are present at high levels in ER-negative and PR-negative breast tumors

IL-1β

3.7

(0–260)

2.2

(0–42.4)

0.031

5.3

(0–194)

2.3

(0–260)

0.008

IL-2

1.7

(0–42.6)

0.9

(0–11.0)

0.003

1.7

(0–6.6)

1.2

(0–42.6)

0.119

IL-4

3.8

(0–20.0)

1.1

(0–99.6)

NS

4.6

(0–18.7)

1.1

(0–99.6)

0.040

IL-6

25.4

(7.8–26,487)

13.2

(4.4–619)

< 0.001

53.6

(9.9–26,487)

13.7

(4.4–4,312)

< 0.001

IL-8

158

(5.0–15,890)

40.5

(0–10,298)

< 0.001

505

(7.3–15,890)

48.7

(0–11,281)

< 0.001

IL-10

0.6

(0–5.6)

0.2

(0–2.86)

0.003

0.8

(0–5.0)

0.2

(0–5.6)

< 0.001

IL-12 (p70)

3.0

(0 -19.3)

2.0

(0–17.2)

0.029

3.1

(0–7.3)

2.0

(0–19.3)

0.024

IL-13

4.3

(3.4–52.6)

4.1

(1.6–394)

0.049

4.3

(3.6–35.5)

4.1

(1.6–394)

NS

G-CSF

17.3

(7.1–110)

20.1

(5.3–87.3)

NS

24.1

(7.1–110)

17.4

(5.3–103)

0.056

IFN-γ

32.6

(19.4–324)

25.6

(15.5–1,279)

< 0.001

33.8

(23.7–324)

25.6

(15.5–1,279)

0.002

MCP-1

210

(14.7–37,117)

80.7

(0–1,543)

< 0.001

404

(17.7–37,717)

96.3

(0–1,543)

< 0.001

MIP-1β

748

(42.6–14,439)

488

(87.2–10,244)

0.005

1121

(44.6–13,287)

493

(42.6–14,439)

0.001

TNF-α

8.5

(6.1–80.0)

6.9

(5.8–120)

< 0.001

8.6

(6.2–37.2)

7.1

(5.8–121)

0.002