Table 2 Hazard ratio (HR) between genotypes and randomisation calculated with the Cox proportional-hazard model

CYP3A5*1/*1, *1/*3

1.00 (16)

1.00 (13)

CYP3A5*3/*3

2.84 (83)

0.68–11.99

0.15

0.20 (95)

0.07–0.55

0.002

CYP2D6*1/*1

1.00 (72)

1.00 (79)

CYP2D6*1/*4, *4/*4

0.87 (31)

0.38–1.97

0.74

0.33 (32)

0.08–1.43

0.14

SULT1A1*1/*2, *2/*2

1.00 (71)

1.00 (73)

SULT1A1*1/*1

0.33 (32)

0.12–0.96

0.04

0.83 (36)

0.29–2.36

0.73

UGT2B15*1/*1

1.00 (17)

1.00 (26)

UGT2B15*1/*2, *2/*2

1.18 (62)

0.39–3.52

0.77

1.94 (55)

0.53–7.06

0.31