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Table 1 Clinicopathological characteristics of patients, primary breast tumours, and treatment

From: p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast cancer

  

Number of patients (percentage)

Total number of patients

 

73

Age at diagnosis (years)

≤50

>50

34 (46.6)

39 (53.4)

 

Range

29 to 77

Tumour size (cm)

<2.0

≥2.0

20 (27.4)

53 (72.6)

Number of positive lymph nodes

0

1–3

>3

21 (28.8)

20 (27.4)

32 (43.8)

Histological grade

1

2

3

12 (16.4)

42 (57.5)

19 (26.1)

Adjuvant therapy

None

Endocrine therapy

Chemotherapy

Combined

5 (6.9)

32 (43.8)

2 (2.7)

34 (46.6)

Disease-free interval (months)

Mean ± SD

Median

39.8 ± 25.7

38

 

Range

2 to 123

First-line endocrine therapy for metastatic breast cancer

Tamoxifen

Aromatase inhibitors

LHRH agonist

LHRH agonist + tamoxifen

Fulvestrant

56 (76.7)

9 (12.3)

3 (4.1)

4 (5.5)

1 (1.4)

  1. LHRH, luteinising hormone-releasing hormone; SD, standard deviation.