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Figure 2 | Breast Cancer Research

Figure 2

From: Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts

Figure 2

Classic isobologram at IC50: rapamycin plus CN-A in MCF-7 cells. Isoboles for the combination of rapamycin with CN-A that were isoeffective (IC50) for inhibition of proliferation of MCF-7 cells. The dashed line indicates the zero interaction of the isobole. Cells (3 × 104 cells/ml) were treated with rapamycin and CN-A for 5 days. Values are the means of three separate experiments. CN-A, cotylenin A; IC50, the concentration of the drug required for 50 % inhibition of cell growth.

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Breast Cancer Research

ISSN: 1465-542X

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