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Figure 1 | Breast Cancer Research

Figure 1

From: Endocrinology and hormone therapy in breast cancer: New insight into estrogen receptor-α function and its implication for endocrine therapy resistance in breast cancer

Figure 1

Nuclear ER-α functions. (a) Enhanced transcription of genes with an estrogen response element (ERE) in the promoter. (b) Enhanced transcription of genes by modifying activity of transcription complexes at other promoter sites (activator protein [AP]-1). AIB, amplified in breast cancer; At, acetyltransferase; E, estradiol; ER, estrogen receptor-α.

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Breast Cancer Research

ISSN: 1465-542X

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