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Table 2 Haplotype distribution of 53BP1 polymorphismsa in breast cancer patients and control individuals

From: TP53-binding protein variants and breast cancer risk: a case-control study

 

Cases

Controls

ORb

95 % CI

P

Haplotype 1059C>G-1234G>A-1347_1352-/+-3406A>C

No. (%)

Mean posterior probability

No. (%)

Mean posterior probability

   

CG+A

444 (68.1)

1

1242 (67.5)

1

1

-

-

CG+C

2 (0.3)

1

1 (0.1)

1

n.a.

n.a.

n.a.

CG–A

6 (0.9)

0.90

25 (1.4)

0.99

0.63

0.23–1.75

0.38

GG+A

1 (0.2)

1

1 (0.1)

1

n.a.

n.a.

n.a.

GG+C

125 (19.2)

1

376 (20.4)

1

1.02

0.79–1.33

0.86

GA+C

74 (11.3)

1

195 (10.6)

1

1.15

0.83–1.61

0.41

  1. aPolymorphisms D353E (1059C>G), G412S (1234G>A), 1347_1352delTATCCC, and K1136Q (3406A>C). b1059C-1234G-1347_1352+-3406A as reference. CI, confidence interval; n.a., not available; OR, odds ratio.