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Fig. 6 | Breast Cancer Research

Fig. 6

From: 18F-fluorodeoxyglucose (FDG) PET or 18F-fluorothymidine (FLT) PET to assess early response to aromatase inhibitors (AI) in women with ER+ operable breast cancer in a window-of-opportunity study

Fig. 6

Percent and absolute change in FDG and FLT SUVmax, and post-therapy Ki-67. Vertical dashed line at pre-specified Ki-67 threshold of 10%; horizontal dotted lines at pre-specified thresholds for response as defined in the Methods. Plotting symbols diameters are proportional to uptake of the PET tracer at baseline. With concordance of %change in SUVmax and post-therapy Ki-67, all data points would appear in the lower left and upper right quadrants. The lesions that do not follow this pattern (upper left and lower right quadrants) are not restricted to those with very low baseline uptake

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