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Fig. 5 | Breast Cancer Research

Fig. 5

From: Plasma cell-free DNA (cfDNA) as a predictive and prognostic marker in patients with metastatic breast cancer

Fig. 5

Kaplan–Meier estimates of probability of progression-free survival in patients with metastatic breast cancer. Comparison between patients with higher/lower A circulating tumour cells (p = 0.007; chi-square = 7.360; hazard ratio = 1.621; 95% CI for HR = 1.102-2.384), B circulating free DNA (p = 0.014; chi-square = 6.084; hazard ratio = 1.555; 95% CI for HR = 1.055–2.292), C CA15-3 (p = 0.006; chi-square = 7.689; hazard ratio = 1.607; 95% CI for HR = 1.113–2.319) and D AP (p = 0.019; chi-square = 5.494; hazard ratio = 1.556; 95% CI for HR = 1.034–2.340). p value obtained by the log-rank test. Hazard ratio and 95% CI obtained by Cox proportional-hazards regression analysis

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