Skip to main content
Fig. 1 | Breast Cancer Research

Fig. 1

From: Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy

Fig. 1

HLA class I HC immunohistochemistry in the GeparTrio cohort: HLA class I HC immunohistochemistry showed a membranous staining pattern. Examples of a positive case and a negative case are shown in the upper and lower half, respectively (a). The data distribution of the immunoreactive score (IRS) as a function of staining quantity (percentage) and quality (intensity) is shown. The colored bars represent the different breast cancer subtypes (b). HLA I was more frequently high in HR−/HER2− breast cancer as compared to other subtypes (c). It was also associated with higher tumor grade, tumor-infiltrating lymphocytes, and nodal status (d)

Back to article page