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Table 1 Patient and lesion characteristics

From: Diffusion tensor imaging for characterizing tumor microstructure and improving diagnostic performance on breast MRI: a prospective observational study

Patients (N = 194)

Value

Age, years

51 (23–83)

Menopausal status

 Pre

93 (47.9)

 Post

101 (52.1)

Indication

 New cancer

126 (64.9)

 Screening/problem solving

68 (35.1)

Breast density

 Fatty

5 (2.6)

 Scattered fibroglandular

47 (24.2)

 Heterogeneously dense

108 (55.7)

 Dense

34 (17.5)

Background parenchymal enhancement

 Minimal

58 (29.9)

 Mild

79 (40.7)

 Moderate

37 (19.1)

 Marked

20 (10.3)

Lesions per patient

 1 lesion

157 (80.9)

 2 lesions

30 (15.5)

 3 lesions

7 (3.6)

Lesions (N = 238)

Largest diameter, cm

 < 1.0 cm

98 (41.2)

 1.0–1.9 cm

71 (29.8)

 2.0–3.9 cm

38 (16.0)

 ≥ 4.0 cm

31 (13.0)

Type

 Mass

135 (56.7)

 NMLE

99 (41.6)

 Focus

4 (1.7)

Delayed phase kinetics(most suspicious)

 Persistent

6 (2.5)

 Plateau

34 (14.3)

 Washout

198 (83.2)

BI-RADS

 4

218 (91.6)

 5

20 (8.4)

Histopathology

 Malignant

95 (39.9)

 Benign

143 (60.1)

Cancer subtype (n = 90*)

 Invasive

73 (81.1)

 DCIS

17 (18.9)

Benign subtype (n = 143)

 Fibroadenoma

25 (17.5)

 Fibrocystic changes

21 (14.7)

 Fibrosis

14 (9.8)

 Usual ductal hyperplasia

12 (8.4)

 Apocrine metaplasia

11 (7.7)

 Lobular neoplasia (LCIS, ALH)

9 (6.3)

 Papilloma

9 (6.3)

 Adenosis

8 (5.6)

 Pseudoangiomatous stromal hyperplasia

6 (4.2)

 Inflammation

5 (3.5)

 Atypical ductal hyperplasia

4 (2.8)

 Fibroadenomatoid change

4 (2.8)

 Normal breast tissue

4 (2.8)

 Other miscellaneous

11 (7.7)

  1. Values are median (range) or no. (%)
  2. NME non-mass enhancement, DCIS ductal carcinoma in situ, LCIS lobular carcinoma in situ, ALH atypical lobular hyperplasia
  3. *Five malignancies did not have a cancer subtype available