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Table 1 Disease status of breast tissue examined in this study

From: Disrupted circadian clocks and altered tissue mechanics in primary human breast tumours

Patient number

Age (years)

Ethnicity

BMI

Tumour details

Histology

Grade

Size (mm)

ER

PR

Her2

Her2 status

Overall tumour phenotype

Patient-1

46

White

33.7

Left breast - lower outer quadrant (LOQ)

IDC

2

23

6

8

1

Neg

ER/PR/Her2-Neg

Patient-2

77

White

36.9

Left breast - upper outer quadrant (UOQ) Mass 29 mm + 2 similar densities USS - 26 mm 3 o’clock - 21 mm

Sarcomastoid/spindle cell/metaplastic carcinoma

3

22

     

Patient-3

78

 

27.8

Right breast - upper half

IDC

3

70

0

0

1

Neg

ER/PR/Her2-Neg

Patient-4

55

white

38.6

Right breast - UOQ. MRI scan

ILC

2

62

8

7

1

Neg

ER/PR/Her2-Neg

Patient-5

69

 

37.2

Left breast - UOQ 3 cm

Invasive mucinous carcinoma

3

50

5

0

3

Pos

ER/Her2

Patient-6

67

White

34.3

Left Breast - UOQ - 2 o’clock. T2 N0

IDC

2

22

8

7

0

Neg

ER/PR/Her2-Neg

Patient-7

53

 

34.4

Right breast lobular cancer

ILC, multifocal

2

52

8

7

1

Neg

ER/PR/Her2-Neg

Patient-8

52

White

28.7

Left Breast - UOQ

Lobulated mass IDC

2/3

24

8

0

2 (non-amp)

Neg

ER/Her2-Neg

  1. Details of the age, ethnicity, body mass index (BMI), and tumour status of breast tissue were analysed. We used breast tumour material, plus normal tissue from the same breast that was located at least 4 cm from the tumours
  2. Abbreviations: ER oestrogen receptor, PR progesterone receptor, Her2 human epidermal growth factor receptor, IDC invasive ductal carcinoma, Neg negative, MRI magnetic resonance imaging, non-amp non amplified