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Fig. 3 | Breast Cancer Research

Fig. 3

From: The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

Fig. 3

Whole genome CNV profiles of chemoradiation-naïve TNBCs with low levels of PD-L1 and PD-1 expression. TNBCs with low levels (IHC score ≤2) of PD-1 and PD-L1 and high levels of CNVs throughout their genomes (top to bottom: TNBCs, 11, 17, 18, 20, and 30). PD-L1 staining location (NT non-tumor cells, T/NT tumor plus non-tumor cells) as well as the DNA ploidy (N) of each TNBC are presented. The X and Y axes in the Comparative Genomic Hybridization plots represent chromosome and log2 ratios for each TNBC. Abbreviations: CNV copy number variant, IHC immunohistochemistry, TNBC triple-negative breast cancer

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