Breast Cancer Research

Table 1 Characteristics of patients with early breast cancer

From: Circulating microRNAs in the early prediction of disease recurrence in primary breast cancer

	All patients		No relapse		Relapse
Characteristic	Number	Percentage	Number	Percentage	Number	Percentage	P
Number of patients	133		84	63	49	37
Age (years)							ns^a
Median	54		52		56
Range	27–79		35–79		27–75
Menopausal status							ns^a
Premenopausal	57	42,9	40	47.6	17	34.7
Postmenopausal	76	57.1	44	52.4	32	65.3
Tumor size (cm)							0.015^a
T1	60	45.1	42	50	18	36.7
T2	66	49.6	41	48.8	25	51
T3	7	5,3	1	1.2	6	12.3
Histological grade							ns^a
I	6	4.5	6	7.1
II	59	44.5	41	48.8	18	36.7
III	58	43.6	31	36.9	27	55.1
Lobular	5	3.7	3	3.6	2	4.1
Unknown	5	3.7	3	3.6	2	4.1
Infiltrated lymph nodes							0.001^a
0	49	36.8	37	44.0	12	24.5
1–3	44	33.1	28	33.3	16	32.7
≥ 4	34	25.6	13	15.5	21	42.8
Unknown	6	4.5	6	7.2
ER status
Positive	88	66.2	56	66.7	32	65.3
Negative	43	32.3	26	31	17	34.7	ns^a
Unknown	2	1.5	2	2.3
PR status							ns^a
Positive	90	67.7	61	72.6	29	59.2
Negative	41	30.8	21	25	20	40.8
Unknown	2	1.5	2	2.4
HER2 status							ns^a
Positive	15	11.3	7	8.3	8	16.3
Negative	112	84.2	72	85.7	40	81.6
Unknown	6	4.5	5	6	1	2.1
Adjuvant chemotherapy							ns^a
Anthracycline-based	13	9.8	9	10.7	4	8.2
Taxanes+anthracyclines	90	67.7	51	60.7	39	79.6
Taxane-based	21	15.8	15	17.9	6	12.2
Others	9	6.7	9	10.7
Hormone therapy							ns^a
Yes	103	77.5	68	80.9	35	71.4
No	28	21.0	14	16.7	14	28.6
Unknown	2	1.5	2	2.4

ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2, ns not significant
^aPearson’s chi-squared test for comparison between patients with relapse and without relapse

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