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Table 3 Mean amide proton transfer (APT) signal in the tumor before and after the first cycle of neoadjuvant chemotherapy (NAC)

From: Amide chemical exchange saturation transfer at 7 T: a possible biomarker for detecting early response to neoadjuvant chemotherapy in breast cancer patients

Patient Pathological response Mean (± SD) APT signal before NAC Mean (± SD) APT signal after the first cycle of NAC Delta mean APT signal P valuea
1 5 0.0494 (± 0.0062) 0.0388 (± 0.0046) − 0.0106 < 0.0001*
2 3 0.0319 (± 0.0046) 0.0311 (± 0.0056) −0.0008 0.0458*
3R 4 0.0289 (± 0.0055) 0.0231 (± 0.0046) −0.0058 0.0004*
3L 4 0.0189 (± 0.0020) 0.0149 (± 0.0034) −0.0040 0.0003*
4 5 0.0420 (± 0.0098) 0.0275 (± 0.0043) −0.0145 < 0.0001*
5 2 0.0132 (± 0.0037) 0.0140 (± 0.0040) +0.0008 0.5749
6 4 0.0272 (± 0.0049) 0.0229 (± 0.0053) −0.0043 0.4135
7 5 0.0254 (± 0.0056) 0.0252 (± 0.0043) −0.0002 0.5259
8 3 0.0319 (± 0.0068) 0.0326 (± 0.0054) +0.0007 0.4170
9 2 0.0381 (± 0.0045) 0.0465 (± 0.0072) +0.0084 0.0001*
  1. aUnpaired Mann-Whitney test with two-tailed distribution
  2. *Significant difference