Fig. 1
MR imaging dataset from patient 1 (see Table 1). a The last image of the DCE series was used to aid in drawing the ROI in the tumor. b S0 image (acquired at 33.6 ppm) was used to draw the tumor ROI (green circle) before applying this on the APT map. c Calculated APT map on top of the DCE image from the dataset before the patient started with neoadjuvant chemotherapy (NAC) treatment. d Calculated APT map after the first cycle of NAC treatment. The blue circles indicate the insert of the tumor region for better viewing of the underlying APT map. Color bar = percentage of APT effect