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Fig. 4 | Breast Cancer Research

Fig. 4

From: Identification and validation of single-sample breast cancer radiosensitivity gene expression predictors

Fig. 4

Performance of the radiosensitivity signature (RSS) (a) and the 10-gene score (10-GS) (b) in the Nanostring data generated with the targeted radiosensitivity gene expression assay. Tumors classified as a case by RSS, or above the median 10-GS score, were regarded high risk. The prognostic performance was evaluated with the Kaplan-Meier method and log-rank test for endpoint ipsilateral breast tumor recurrence, stratified for estrogen receptor (ER) status and radiotherapy (RT). The treatment predictive effect was evaluated by analyzing the effect of RT in samples classified as radioresistant or radiosensitive by the respective classifiers (c)

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