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Fig. 6 | Breast Cancer Research

Fig. 6

From: Glucocorticoids promote transition of ductal carcinoma in situ to invasive ductal carcinoma by inducing myoepithelial cell apoptosis

Fig. 6

Effects of glucocorticoids (GC) on ductal carcinoma in situ (DCIS) transition to invasive ductal carcinoma (IDC). Glucocorticoids promote progression of DCIS to invasiveness by reducing laminin levels and inducing myoepithelial cell apoptosis in vitro and in vivo, effects that can be partially blocked by the glucocorticoid receptor antagonist RU486

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