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Table 5 Sensitivity, specificity, PPV, NPV, and AUC of the best set of predictors based on tumor subtype and hemoglobin parameters of the testing data

From: Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters

 

Sensitivity

Specificity

PPV

NPV

AUC

Her2, tHb, %tHb_cyc1

73.7

94.9

92.4

84.8

0.96

Her, tHb, %tHb_cyc1, %tHb_cyc2

82.4

94.9

92.5

86.7

0.97

ER, tHb, %tHb_cyc1

81.8

88.1

85.8

85.1

0.90

TN, tHb, %tHb_cyc1

82.0

88.1

85.9

85.1

0.90

tHb, %tHb_cyc1

83.8

88.1

86.1

86.5

0.95

  1. AUC area under the curve, ER estrogen receptor, HER2 human epidermal growth factor receptor 2, NPV negative predictive value, PPV positive predictive value, tHb total hemoglobin, TN triple negative