Skip to main content

Table 1 Characteristics of breast cancer cases and controls, matched on age and menopausal status

From: Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study

Characteristic Breast cancer cases (n = 62) Controls (n = 177) P
Age at MBI (years)a 60.3 ± 10.6 (38–88) 60.2 ± 10.4 (38–86) NA
Menopausal status    NA
 Premenopausal 13 (21) 38 (22)  
 Postmenopausal 49 (79) 138 (78)
Body mass index (kg/m2)a 27.7 ± 6.4 (18.8–55.5) 26.2 ± 4.7 (18.6–44.3) 0.06
Postmenopausal systemic hormone therapyb    0.57
 Current use at MBI 13 (27) 44 (31)  
 No current use at MBI 36 (73) 97 (69)  
BI-RADS density    0.81
 Almost entirely fat 1 (2) 3 (2)  
 Scattered fibroglandular densities 10 (16) 34 (19)
 Heterogeneously dense 44 (71) 113 (64)
 Extremely dense 7 (11) 26 (15)
Percent densitya 24.8 ± 8.3 (3.5–48.0) 24.6 ± 10.2 (1.8–53.8) 0.93
Tumor invasiveness
 Invasive 45 (73) NA  
 DCIS 17 (27) NA
Gail model 5-year riska 2.7 ± 1.5 (0.6–7.2) 2.4 ± 1.5 (0.5–9.5) 0.23
BCSC model 5-year riska 2.6 ± 1.2 (0.7–5.4) 2.3 ± 1.5 (0.4–13.2) 0.29
Family history of breast cancer    0.45
 One or more first-degree relatives 33 (53) 86 (48)  
 No first-degree relatives 29 (47) 93 (52)
Personal history of biopsy showing atypia or LCIS    0.07
 Yes 6 (10) 6 (3)  
 No 56 (90) 173 (97)
  1. Unless otherwise noted, data are number of patients and data in parentheses are percentages
  2. aData are mean ± standard deviation; data in parentheses are the range
  3. bData are among postmenopausal women only (49 breast cancer cases; 138 controls)
  4. BCSC, Breast Cancer Surveillance Consortium; BI-RADS, Breast Imaging-Reporting and Data System; DCIS, ductal carcinoma in situ; LCIS, lobular carcinoma in situ; MBI, molecular breast imaging; NA, not available