Fig. 6
From: Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer
Phosphatase and tensin homolog (PTEN) and serine/threonine kinase 11 (STK11) mutations are mutually exclusive in tumors. OncoPrints show deep (homozygous) deletions, fusions, small insertions and deletions, and non-silent single-base-substitution mutations detected by MSK-IMPACT in all patients studied (a) and in the subset of patients with breast cancer within the cohort (b). Mutual exclusivity of mutations was determined using odds ratios and the Fisher exact test. Only tumors with mutations are shown