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Table 6 Association between treatment and changea in %MD

From: The association of mammographic density with risk of contralateral breast cancer and change in density with treatment in the WECARE study

  

Adjusted for age and BMIb

Adjusted for age, BMIb, and other treatments

 

Number

Estimated %MD changec

95% CI

p

Estimated %MD changec

95% CI

p

Radiation

       

 No

142

Reference

  

Reference

  

 Yes

325

0.2

−2.1, 2.5

0.89

0.7

−1.6, 3.0

0.57

Chemotherapy

       

 No

161

Reference

  

Reference

  

 Yes

306

−2.9

−5.1, −0.7

0.01

−3.0

−5.2, −0.8

0.008

Tamoxifen

       

 No

238

Reference

  

Reference

  

 Yes

229

−2.8

−4.9, −0.7

0.009

−3.0

−5.1, −0.9

0.006

  1. Abbreviations: %MD percent mammographic density, BMI body mass index, CI confidence interval
  2. aBetween prior to/at first diagnosis (36 months prior up to 1 month post diagnosis) and post diagnosis (more than 6 and up to 48 months post diagnosis)
  3. bEstimated BMI at time of mammogram
  4. cEstimated change in %MD (post diagnosis minus prior to/at diagnosis) associated with each treatment modality