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Fig. 3 | Breast Cancer Research

Fig. 3

From: The origins of breast cancer associated with mammographic density: a testable biological hypothesis

Fig. 3

Proposed model of the two-stage model of carcinogenesis with risk of breast cancer in percent mammographic density. (The third column represents effects on the growth of a clone of malignant cells.) CAF Cancer-associated fibroblast, ECM Extracellular matrix, HGF Hepatocyte growth factor, IGF-1 Insulin-like growth factor 1, MMP-3 Matrix metalloproteinase 3, TGF-β Transforming growth factor-β

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